Fabric Phase Sorptive Extraction in Pharmaceutical Analysis

Fabric Phase Sorptive Extraction in Pharmaceutical Analysis

Micro extraction techniques represent the current state of the art in analytical sample preparation characterized with solvent-free/solventminimized extraction, miniaturization and automation to treat samples with pharmaceutical, food, forensic, and environmental significance for instrumental analysis. To be consistent with today’s challenges of sustainability and environmental issues, Green An...

Stir bar-sorptive extraction, solid phase extraction and liquid-liquid extraction for levetiracetam determination in human plasma: comparing recovery rates

Levetiracetam (LEV), an antiepileptic drug (AED) with favorable pharmacokinetic profile, is increasingly being used in clinical practice, although information on its metabolism and disposition are still being generated. Therefore a simple, robust and fast liquid-liquid extraction (LLE) followed by highperformance liquid chromatography method is described that could be used for both pharmacokine...

Speciation of Cr (III) and Cr (VI) Ions via Fabric Phase Sorptive Extraction for their Quantification via HPLC with UV Detection

Simultaneous extraction of the morpholino dithiocarbamate (MDTC) chelates of Cr(III) and Cr(VI) ion from aqueous samples was accomplished by applying fabric phase sorptive extraction (FPSE) using a cellulose fabric modified with a sol-gel/polytetrahydrofuran composite. Following extraction, the chelates were separated by HPLC on a reverse phase C18 column with acetonitrile:water (65:35; v/v) as...

Stir Bar Sorptive Extraction (SBSE) applied to Environmental Aqueous Samples

Elimination of Polar Matrix Compo- nents Prior to GC Analysis using Stir Bar Sorptive Extraction (SBSE)

Analysis of samples containing polar matrix components such as water, glycols, sugars or surfactants by gas chromatography has usually required extensive cleanup such as liquid/liquid extraction, solid phase extraction or distillation. Some polar matrix components like acetic acid or ethanol are highly volatile and difficult to eliminate using traditional sample preparation techniques. Poor ana...